世界首例干細(xì)胞治療早產(chǎn)兒視網(wǎng)膜病變(ROP) 美國(guó)母親寫博客贊干細(xì)胞療效
來(lái)源:干細(xì)胞科學(xué)網(wǎng)
美國(guó)患者Tatyana Larbi,女,2003年11月2日出生,電子郵箱hope4vision@hotmail.com,電話7708330620,患早產(chǎn)兒視網(wǎng)膜病變(5期)來(lái)城陽(yáng)人民醫(yī)院干細(xì)胞治療康復(fù)中心就醫(yī),接受干細(xì)胞治療。
早產(chǎn)兒視網(wǎng)膜病變(ROP)是未成熟或低體重出生嬰兒的一種視網(wǎng)膜病變。大部分早產(chǎn)兒生后可能會(huì)有視網(wǎng)膜的不成熟改變,隨著時(shí)間的推移而逐漸自行發(fā)育成熟;但是有少數(shù)患兒出生時(shí)體重較低,或胎齡較小,加之吸氧時(shí)間較長(zhǎng)、有呼吸系統(tǒng)疾病或合并有其它高危因素等等則可能患上早產(chǎn)兒視網(wǎng)膜病變。
早產(chǎn)兒視網(wǎng)膜病變的危害程度取決于三個(gè)方面(1)病變的分區(qū):視網(wǎng)膜分為Ⅰ、Ⅱ、Ⅲ區(qū),Ⅰ區(qū)病變最重,預(yù)后最差,Ⅲ區(qū)病變最輕,預(yù)后最好;(2)病變的分期:按嚴(yán)重程度分為5期,5期影響視力最明顯;(3)有無(wú)Pl(wèi)us病變的存在,如有則預(yù)示著病變活動(dòng)性強(qiáng),惡化迅速。
有些早產(chǎn)兒視網(wǎng)膜病變可以自行回退,影響視力可能較輕微,但是如果達(dá)到需要治療的階段而未得到適時(shí)的治療,患兒視力就可能永久性喪失,并且有可能繼發(fā)青光眼、角膜白斑、角鞏膜葡萄腫、眼球萎縮等嚴(yán)重并發(fā)癥,最終影響面部發(fā)育。
我們持續(xù)關(guān)注該患者在接受干細(xì)胞治療之后的改善情況,一個(gè)月后,她媽媽寫了這篇博客,我們翻譯過(guò)來(lái)給大家了解患者的病情改善情況。
Before And After
March 30th, 2009 by tatyana
I would like to call this blog “Before And After” (stem cell treatment).
我喜歡稱這個(gè)博客為“前與后”
BEFORE, if Tatyana wanted a glass of water she would ask and I would get it for her. Then if she wanted more I would get up
again to get it for her and so on.
以前:如果TATYANA 想要一杯水,她會(huì)說(shuō),我會(huì)給她拿。然后我要再次的起來(lái)給她拿如果她還要的話。
NOW, if she wants water I get her the cup and put water in it. She drinks it, puts it on the counter, if she wants more she
goes to counter and gets more. She loves to do this so she repeats it over and over again until the water is gone.
現(xiàn)在,如果她想喝水,我把倒了水的杯子給她,她喝了,然后把杯子放在柜子上,如果她想喝更多,她自己會(huì)拿,她喜歡不斷的重復(fù)這個(gè)動(dòng)作,直到把杯子里的水喝完。
BEFORE, Tatyana would throw her clothes on the floor and mommy would pick them up and put them in the hamper.
以前:TATYANA會(huì)把衣服仍在地板上,媽媽會(huì)撿起衣服并放到贓物藍(lán)里。
NOW, Tayana still throws her clothes on the floor (hehehehe) but this time I tell her to pick them up and put them in the hamper.
She walks over to were she threw them down, picks it up, walks to the hamper to put them in. She is a typical 5 yr old toddler so
she plays along the way so she may need some reminders to complete the task but she does it which is the best part.
現(xiàn)在:TAYANA仍然喜歡把衣服扔在地板上,但是這次,我告訴她撿起他們并放到贓物藍(lán)里,她走到她扔衣服的地方,撿起他們,走到贓物藍(lán)那里并把衣服放進(jìn)去。她是一個(gè)典型的5歲的蹣跚學(xué)步的女孩,她以自己的方式玩耍,她也許需要一些提醒解釋工作,但是她做了就是最好的部分。
BEFORE, in church Tatyana would sit in mommy’s lap scared to sit in the seats next to me. If I tried to put her in the seat she would jump back in my lap.
以前:在教堂,TATYANA會(huì)坐在我的膝蓋上,害怕坐在我旁邊的位子上,如果我累了,把她放到位子上她會(huì)跳回到我的膝蓋上。
NOW, in church Tatyana sits in the seat next to me, greets the person sitting next to her, she is quiet, she stares at the person
next to her to see what they are doing. My thoughts are she is more aware of her surroundings and understands what people do in
church which is sitting quietly, listening or reading their Bible.
現(xiàn)在:在教堂里,Ttyana坐在我旁邊的位子上,歡迎別人坐在她的旁邊,她很安靜,她盯著坐在她旁邊的人,看他們?cè)谧鍪裁础N业南敕ㄊ撬_始意識(shí)和理解為什么人們安靜的坐在教堂里傾聽或是朗讀他們的圣經(jīng)。
BEFORE, if I would hand Tatyana an object she wouldn’t know something was in front of her. I would tell her I am giving her something or I would have to put it in her hand.
以前:如果我要拿給TATYANA 一個(gè)她并不知道的東西在她面前,我會(huì)告訴她我要給她一些東西或者我必須放到她的手里。
NOW, I can hold something up in front of her and she can grab it out of my hand. I can also hold up something like a tissue box
and not only does she see the tissue box she KNOWS its a tissue box and reaches to pull out a tissue.
現(xiàn)在:我可以在她的面前拿著什么東西,她能從我的手中搶走它。我也可以拿著東西像紙巾盒,她不僅看到了紙巾盒,她知道那是個(gè)紙巾盒并要拿紙巾。
BEFORE, her left eye was her weakest eye. She had no vision out of that eye except light.
以前:她的左眼是最弱的眼睛。除了光感沒(méi)有視力。
NOW, her left eye is her strongest eye. When she looks at things I can tell she using her left eye the most. She even looks inside
bags or cups pointing her left eye in the bag or cup to see what’s in the bag or cup.
現(xiàn)在:她的左眼是她的最強(qiáng)壯的眼睛。當(dāng)他看東西的時(shí)候我可以告訴他多用她的左眼。甚至當(dāng)他看包和杯子里的時(shí)候,她重點(diǎn)用她的左眼去看到底有些什么在包里和杯子里。
GO little Stem Cells GO!!!!
加油小細(xì)胞們,加油!!!
These are just a few things I have noticed. It will take time for her vision to improve more. I tried teaching her colors but she
is not understanding that quite yet. I am not discouraged, that will come with time.
Thanks for listening and I will keep you posted on her progress.
這些只是我注意到得一些事。還需要一些時(shí)間讓她的視力得到更多的改善。教她辨認(rèn)顏色使我很累,但是她還沒(méi)有十分的明白,我并沒(méi)有氣餒,因?yàn)槟且惶煲欢〞?huì)到來(lái)的。
謝謝你們的傾聽,我會(huì)隨時(shí)讓大家了解她的進(jìn)步。